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Carol L. (Canada) I have no idea about the Alto Advanced Defense as I haven't tried it yet . However; i did use the old version and loved it. I have to say Signature Med Spa was wonderful. They shipped very securely and gave samples of other items to try. I love this because it helps you decide if you should try other products. Let's face it, we are all trying to look our best for as long as we are able. Kudos your team!!!