The Ultimate Power Pair is now available at Signature Cosmetic Clinic
Introducing the NEW SkinCeuticals P-TIOX Serum + P-TIOX Cream duo, designed to help smooth the appearance of fine lines, wrinkles and pores while enhancing your skin’s natural radiance.
SkinCeuticals has just launched P-TIOX Cream, the newest addition to its P-TIOX line, joining the already well loved P-TIOX Serum. Often nicknamed a "topical Botox alternative," the P-TIOX line was developed to visibly soften expression lines at home, while also extending and enhancing the results of in-clinic neurotoxin treatments for those who prefer injectables. Offensive or defensive, at home or alongside professional treatment, it is designed to work with your routine. Signature Cosmetic Clinic one of the authorized provider, and the newly launched P-TIOX Cream is now available in clinic alongside the serum.
How Expression Lines Actually Form
Expression lines, also called contraction lines, form from the repeated pull of facial muscles every time we smile, frown, squint, or raise our brows. Over years, this constant movement, combined with the natural breakdown of collagen and elastin, turns temporary creases into visible, static lines around the eyes, forehead, cheeks, and mouth. Traditional neurotoxin injections address this by relaxing the muscle at the injection site. P-TIOX works topically to help calm the signaling that drives repeated muscle contraction, while simultaneously supporting the skin's structure from the surface down.
P-TIOX Serum: Anti-Wrinkle and lines
Since its launch, P-TIOX Serum has become one of SkinCeuticals' best selling corrective treatments, and it remains the foundation of the P-TIOX line. It is built around a dual peptide complex, combining 2% Acetyl Hexapeptide-8 with 2% Dipeptide (a peptide with a snake venom inspired mechanism). Together, these peptides are formulated to help modulate the neurotransmitter activity and muscle contraction factors involved in expression line formation, working in a way that has been compared to the effect of neuromodulator injections, without needles.
The peptide complex is amplified by three synergistic actives:
- 5% PHA (Gluconolactone), a gentle polyhydroxy acid that resurfaces the skin and speeds cell turnover without the irritation associated with stronger acids
- 5% Niacinamide (Vitamin B3), which strengthens the skin barrier, evens tone, and supports the peptide complex's collagen boosting effect
- Laminaria (sea kelp) Extract, a marine derived ingredient that hydrates, soothes, and helps lock in moisture
Clinical Results for the Serum
SkinCeuticals conducted a 12 week, single center clinical study on 82 women with Fitzpatrick skin types I through VI, ages 34 to 65, more than half of whom had sensitive skin. Skin was evaluated by a dermatologist at baseline, and again at weeks 1, 2, 4, 8, and 12. The study tracked visible improvement across all nine targeted expression line types, along with skin smoothness, radiance, and pore appearance.
Reported outcomes included:
- Visible improvement in skin smoothness and pore refinement within just 1 week of use
- A global reduction in fine lines of up to roughly 20% by week 12
- In a separate study on 50 Asian women, forehead lines were reduced by as much as 68%, under eye lines by around 38%, and lines around the mouth by approximately 43% after 4 to 12 weeks of consistent use
While results vary by individual, the consistent pattern across studies is fast improvement in texture and glow, followed by progressive line softening that builds over two to three months.
P-TIOX Cream: The New Launch
P-TIOX Cream is the brand new moisturizing companion to the serum. Where the serum focuses on expression lines, the cream was formulated to go further, targeting deeper set, more static wrinkles, enlarged pores, and overall skin quality. Its patent pending formula is built on:
- 10% Myrixin, a proprietary complex of six plant extracts concentrated in myricetin, formulated to smooth the appearance of deep set lines and support long term skin refinement
- 2% Tripeptide Complex, targeted at softening the look of contraction lines caused by repetitive facial movement
- Niacinamide, Crystalide micropeptide, LHA, and Zinc PCA, which work together t
The cream uses a micro melting texture that absorbs quickly into the skin, delivering long lasting comfort without any greasy after feel, which makes it suitable for normal, combination, oily, and sensitive skin types alike.
Clinical Results for the Cream
In its own 12-week clinical evaluation, P-TIOX Cream showed:
- Wrinkles visibly reduced by up to 33%
- Pore size visibly reduced by up to 30%
- Overall skin quality, smoothness, and tone evenness improved by up to 30%
When the cream is layered with the serum, the combined routine is designed to deliver visible glass skin radiance in as little as one week, with continued improvement in texture and fine lines through the full 12 week period.
How to Use P-TIOX Serum and Cream Together
For the full glass skin routine, both products are intended to be used together, morning and evening:
- Cleanse the skin
- Apply 4 to 6 drops of P-TIOX Serum, smoothing it across the forehead, cheeks, chin, and any other areas of concern
- Follow with P-TIOX Cream, gently pressing it into the face, neck, and eye area until fully absorbed
- In the morning, always finish with a broad spectrum sunscreen
Both products have been physician tested to complement in-clinic neurotoxin injections and dermal filler treatments, making them a natural at-home extension of your professional treatment plan. They are also gentle enough to use on their own, without any injectable treatment, for those who prefer a fully needle free approach to expression line correction.
What Our Clients Are Saying
I’m genuinely impressed with the results. In just a few applications my skin looked smoother and more refined, like I had a subtle filter effect. Just ordered my second P-Tiox and will continue ordering again. Definitely worth it and highly recommend! - Elly
Great anti aging serum. This serum can be use on the eye area as well, works great on fine lines - Nikki L.
Available Now at Signature Cosmetic Clinic
As an authorized SkinCeuticals provider, Signature Cosmetic Clinic now offers the newly launched P-TIOX Cream. Our team is here to help you build the right routine for your skin.
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